Alison Young

Craftalot said:

The main study into the effectiveness of semaglutide (Ozempic) was 72 weeks duration. In practice, most pts plateau after about 60 weeks. It's licensed for use for a maximum of 2 years, after which about 98% of patients regain at least two-thirds of the weight they have lost within a year (see link below if you're interested). Even worse, all the cardiometabolic benefits which accompany the weight loss - lower BP, better glucose control and insulin secretion/response, lower LDL cholesterol etc - are entirely reversed once stopping semaglutide. In practice, the overwhelming majority of patients regain all the weight that they had lost, for entirely predictable reasons.

I'd said in a previous post that the acid test as to whether or not she's taking a drug like ozempic (not that it's anyone's business but hers) is if she manages to keep the weight off for about 18-24 months. She's a classic yo-yo dieter, and in previous cycles, she's lost and regained a couple of stone in a 6-9 month period (again, a very classic pattern). If she suddenly loses a lot of weight and manages to keep it off, then you can be pretty sure that something has changed this time...

Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension

To explore changes in body weight and cardiometabolic risk factors after treatment withdrawal in the STEP 1 trial extension.STEP 1 (NCT03548935) randomized 1961 adults with a body mass index ≥ 30 kg/m[2] (or ≥ 27 kg/m[2] ...

www.ncbi.nlm.nih.gov

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Craftalot said:

The main study into the effectiveness of semaglutide (Ozempic) was 72 weeks duration. In practice, most pts plateau after about 60 weeks. It's licensed for use for a maximum of 2 years, after which about 98% of patients regain at least two-thirds of the weight they have lost within a year (see link below if you're interested). Even worse, all the cardiometabolic benefits which accompany the weight loss - lower BP, better glucose control and insulin secretion/response, lower LDL cholesterol etc - are entirely reversed once stopping semaglutide. In practice, the overwhelming majority of patients regain all the weight that they had lost, for entirely predictable reasons.

I'd said in a previous post that the acid test as to whether or not she's taking a drug like ozempic (not that it's anyone's business but hers) is if she manages to keep the weight off for about 18-24 months. She's a classic yo-yo dieter, and in previous cycles, she's lost and regained a couple of stone in a 6-9 month period (again, a very classic pattern). If she suddenly loses a lot of weight and manages to keep it off, then you can be pretty sure that something has changed this time...

Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension

To explore changes in body weight and cardiometabolic risk factors after treatment withdrawal in the STEP 1 trial extension.STEP 1 (NCT03548935) randomized 1961 adults with a body mass index ≥ 30 kg/m[2] (or ≥ 27 kg/m[2] ...

www.ncbi.nlm.nih.gov

Click to expand...

candycane said:

That's right Griz. If you are a genuine diabetic (and CH may well be) then you can take semaglutide for as long as it is prescribed for you. Doctors keep a very close eye on you if you take these drugs to make sure they are doing good and not harm. Mr CC lost all that weight and kept it off as he continued to take the drug. Now he can't get it and he was on insulin (although his diabetes is type 2) but I believe he's now on semaglutide or similar in a tablet form. I think that might be a new drug. Don't shout that out too loudly!

CC

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donna255 said:

Doctors do not just hand out it just because you are suddenly found to have Type 2 diabetes. You will be told to diet Type 2 can be diet controlled, and they try this before moving to tablets.

CHuntly's daughter is getting married, she will want to be thin for the photos as mother of the bride.

AY has had an underactive thyroid for years perhaps 10 or more and when she started putting on weight people on here said that was the reason. It if very difficult to lose weight when you have an underactive thyroid. If the doctor keeps on top of it and gets the meds correct you can lose weight but not as much as AY without help for other sources so quickly.

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Toril said:

I’ve had an underactive thyroid since 2015 and it is difficult to lose weight because of the effect hypothyroidism has on the metabolic rate, despite being on the correct dosage.

However, since February this year I’ve lost over 3 stone and it’s still coming off slowly. I haven’t used, and never would, any weight loss medication or interventions because the weight would probably go back on when the weight loss medication was stopped. I’ve done it by changing to a healthy diet and ditching the biscuits, chocolate, crisps and rubbish that I used to snack on. I don’t feel hungry but do feel a lot healthier which is a bonus and I know that the weight will stay off because it’s been done slowly and healthily. The only drawback is that I’ve had to buy loads of new clothes because the others were hanging off me as they were four sizes too big but it’s been worth it and the Air Ambulance charity has benefited from my “updating” my wardrobe.

It’s also more difficult to lose weight the older you are so, coupled with an underactive thyroid, the odds were against me but, to be honest, I’m surprised (and delighted) that I’ve managed to do it.

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Toril said:

I’ve had an underactive thyroid since 2015 and it is difficult to lose weight because of the effect hypothyroidism has on the metabolic rate, despite being on the correct dosage.

However, since February this year I’ve lost over 3 stone and it’s still coming off slowly. I haven’t used, and never would, any weight loss medication or interventions because the weight would probably go back on when the weight loss medication was stopped. I’ve done it by changing to a healthy diet and ditching the biscuits, chocolate, crisps and rubbish that I used to snack on. I don’t feel hungry but do feel a lot healthier which is a bonus and I know that the weight will stay off because it’s been done slowly and healthily. The only drawback is that I’ve had to buy loads of new clothes because the others were hanging off me as they were four sizes too big but it’s been worth it and the Air Ambulance charity has benefited from my “updating” my wardrobe.

It’s also more difficult to lose weight the older you are so, coupled with an underactive thyroid, the odds were against me but, to be honest, I’m surprised (and delighted) that I’ve managed to do it.

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ERICS MUM said:

Oh the irony of Alison and her 1001 genders, assuming she does it to attract the other 999 to buy her products.

I imagine that only one gender actually watches her shows and buys the over priced products. That same gender might buy for the 2nd gender on the rare occasion men’s ranges are offered.

Somehow I can’t see the other 999 genders being fans of QVC. I’m happy to be persuaded otherwise.

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alter ego said:

AY is the wrong age to lose a lot of weight a the elasticity has gone from her skin.

Orange turnip, err, Trump is repulsive enough. Can you imagine him pasty white?!

Famous charismatic men throughout history have mostly turned out to be power-hungry wrong 'uns. Turnip is out for himself but his cult members, err, followers keep sending money to his causes (usually to get him out of trouble/fund his campaigns). It astounds me. I watch his speeches and can't help but think of Hitler.

Male politicians like Turnip and even Boris all have the 'charisma' to draw people in. I have no idea why people vote for men like this, especially when their personal lives would cause their voters to raise eyebrows and gossip about their neighbours if they behaved like that.

On the other end of the spectrum are men like Starmer. Not an ounce of charisma but gets votes because they lead the party they've always voted for.

Is it the men at fault or the people who blindly follow? I can't help but think of Hitler as he was considered charismatic. I'd like to think nothing like Nazi Germany could never happen again but...

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Patsy said:

Trump has a face like a smacked a##e. Him and his mates Boris and Farage are repulsive misogynists.

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